AT

Acoustic Neuroma (Vestibular Schwannoma) — Practice

Q1.Moderate#Clinical
A 42-year-old man develops progressive bilateral sensorineural hearing loss and intermittent tinnitus. MRI shows bilateral vestibular schwannomas, and he also has a few subcutaneous schwannomas and a posterior subcapsular lens opacity. Mutation in which gene is most likely responsible for this condition?
ANF1 gene on chromosome 17
BRET proto-oncogene on chromosome 10
CVHL gene on chromosome 3
DNF2 (merlin) gene on chromosome 22