Acute Liver Failure
HardMedicine · GIT & Hepatology
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Acute liver failure (ALF) is a catastrophic, potentially reversible syndrome of rapid hepatocellular dysfunction in a patient without pre-existing liver disease, defined by the triad of coagulopathy (INR ≥ 1.5), hepatic encephalopathy, and jaundice evolving within 26 weeks. It is a true medical emergency where the central killer is cerebral oedema and where early identification of transplant candidacy (King's College…
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