Antifungal Agents — Mechanisms & Spectrum
ModerateMicrobiology · Mycology
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Antifungals exploit the few structural differences between the fungal and human cell — chiefly ergosterol (the fungal membrane sterol, in place of human cholesterol) and the β-1,3-glucan cell wall. Knowing which enzyme/structure each class hits and the drug-of-choice (DOC) for each named infection is the single highest-yield axis for NEET PG. Fungi differ from human cells at three exploitable points: the cell memb…
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