Cell Injury & Adaptation — Practice
A 60-year-old man undergoing chemotherapy for high-grade lymphoma develops acute kidney injury, with serum potassium 6.8 mmol/L, phosphate high, calcium low, and urate markedly elevated. Which prophylactic agent acts by converting uric acid to the more soluble allantoin?
AAllopurinol
BSodium bicarbonate
CFebuxostat
DRasburicase