Coenzymes & Enzyme Regulation — Topic Test
20 questions · exam mode (answers revealed at the end). 18 min suggested.
During an experiment on glycolytic regulation in hepatocytes, a glucagon surge is simulated. Which change in the bifunctional enzyme PFK-2/FBPase-2 best accounts for the resulting fall in glycolytic flux?
AAllosteric AMP binding inhibits the FBPase-2 domain
BDephosphorylation activates the PFK-2 domain, raising fructose-2,6-bisphosphate
CPKA-mediated phosphorylation activates the FBPase-2 domain, lowering fructose-2,6-bisphosphate
DPKA phosphorylation activates the PFK-2 domain, raising fructose-2,6-bisphosphate