Fatty Acid Synthesis & Beta-Oxidation — Topic Test
20 questions · exam mode (answers revealed at the end). 18 min suggested.
A previously well 3-year-old becomes hypoglycaemic, hypoketotic and develops cardiomyopathy during a febrile illness. Acylcarnitine profile shows elevated C8 (octanoylcarnitine) and dicarboxylic aciduria. The deficient enzyme acts at which step of mitochondrial fatty acid oxidation?
ACarnitine-dependent entry of long-chain acyl groups
BFirst dehydrogenation of medium-chain acyl-CoA
CHydration of enoyl-CoA
DThiolytic cleavage releasing acetyl-CoA