Fluoroquinolones
ModeratePharmacology · Antimicrobials
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Fluoroquinolones are broad-spectrum, bactericidal, concentration-dependent antibiotics that act by inhibiting bacterial DNA gyrase and topoisomerase IV. They are among the most heavily tested antimicrobials in NEET PG because of their unique mechanism, predictable generation-wise spectrum, classic drug interactions (antacid chelation), and a famous cluster of adverse effects (tendinopathy, QT prolongation, cartilage …
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