Ketone Body Metabolism — Practice
A 32-year-old woman on a strict ketogenic diet for refractory epilepsy is investigated for fasting metabolism. During prolonged starvation, the brain shifts to using ketone bodies. Which enzyme, absent in the liver, prevents hepatocytes from utilising the acetoacetate they themselves export?
A3-hydroxy-3-methylglutaryl-CoA synthase
BAcetoacetate decarboxylase
CBeta-hydroxybutyrate dehydrogenase
DSuccinyl-CoA:3-ketoacid CoA transferase (thiophorase)