Leprosy: Classification & Diagnosis
ModerateHigh-yieldDermatology · Leprosy
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Leprosy (Hansen's disease) is a chronic granulomatous infection by Mycobacterium leprae that selectively targets skin and peripheral nerves. The clinical spectrum is determined entirely by the host's cell-mediated immunity (CMI) — strong CMI gives paucibacillary tuberculoid disease, weak CMI gives multibacillary lepromatous disease. This single immunological axis explains the Ridley-Jopling spectrum, the smear result…
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