Nephrotic Syndrome in Children

Nephrotic syndrome is one of the commonest chronic glomerular disorders of childhood, defined by a quartet of heavy proteinuria, hypoalbuminaemia, oedema and hyperlipidaemia. In children it is overwhelmingly idiopathic, minimal change disease dominates, and the single most important prognostic question is whether the child responds to steroids. Nephrotic syndrome (NS) is a clinical state arising from increased glo…