Organophosphate & Carbamate Poisoning — Practice
A 34-year-old labourer is admitted after spraying an organophosphate insecticide without protection. He has miosis, profuse salivation, bronchorrhoea and fasciculations. Atropine is started. Which laboratory parameter is the most reliable for confirming the diagnosis and grading the severity of organophosphate poisoning?
ASerum (true) red-cell acetylcholinesterase activity
BPlasma pseudocholinesterase measured 48 hours after exposure
CSerum aspartate aminotransferase level
DUrinary delta-aminolaevulinic acid excretion