Pemphigus Vulgaris
ModerateHigh-yieldDermatology · Vesiculobullous
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Pemphigus vulgaris (PV) is the prototype of the intraepidermal autoimmune blistering diseases — a potentially fatal disorder in which IgG autoantibodies attack the desmosomal adhesion protein desmoglein-3, splitting the epidermis just above the basal layer. For NEET PG it is one of the highest-yield dermatology topics: examiners repeatedly test the site of the split, the target antigen, Nikolsky sign, tombstone appea…
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