Purine & Pyrimidine Metabolism
HardBiochemistry · Metabolism
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Purines (adenine, guanine) and pyrimidines (cytosine, thymine, uracil) are the nitrogenous bases of nucleic acids. NEET PG loves this topic for its tight enzyme-deficiency → disease pairings (HGPRT → Lesch-Nyhan, ADA → SCID) and the pharmacology of gout (xanthine oxidase, allopurinol). Master the rate-limiting steps, the salvage enzymes, the end-products, and the drug targets. | Feature | Purines | Pyrimidines | |…
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