Serotonin & Antiserotonin Drugs
ModeratePharmacology · Autacoids
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Serotonin (5-hydroxytryptamine, 5-HT) is a key autacoid acting as a neurotransmitter, vasoactive amine and gut regulator. This chapter consolidates its synthesis, the bewildering family of 5-HT receptors, the major agonists and antagonists, and the two clinical scenarios examiners love: carcinoid syndrome and serotonin syndrome. 5-HT is synthesised from the essential amino acid L-tryptophan in a two-step pathway: …
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