SLE — Systemic Pathology
ModeratePathology · General Pathology
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Systemic lupus erythematosus (SLE) is the prototypic multisystem autoimmune disease driven by immune-complex deposition (type III hypersensitivity) plus some type II (antibody-mediated cytopenias) mechanisms. For Pathology, the examiner cares less about the rheumatology checklist and more about the organ-level morphology — the wire-loop lesion of lupus nephritis, Libman–Sacks endocarditis, serositis, and the haematox…
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