Antiphospholipid Syndrome

Antiphospholipid syndrome (APLS / APS) is an acquired autoimmune thrombophilia defined by arterial or venous thrombosis and/or pregnancy morbidity occurring in the presence of persistent antiphospholipid antibodies (aPL). It is the most common cause of acquired thrombophilia and a favourite of NEET PG examiners for its single most counter-intuitive fact: a clotting disorder that paradoxically prolongs the aPTT in vit…