Systemic Lupus Erythematosus
HardHigh-yieldMedicine · Rheumatology
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Systemic lupus erythematosus (SLE) is the prototypic multisystem autoimmune disease driven by loss of tolerance to nuclear antigens, immune-complex deposition and complement activation. It is overwhelmingly a disease of young women (F:M ~9:1, peak 15–45 years) and is a perennial NEET PG favourite for its criteria, autoantibody specificities and lupus nephritis classification. SLE is a chronic, relapsing–remitting …
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